DZL Annual Meeting 2018

From February 8 to 9, the German Center for Lung Research will hold its Annual Meeting 2018 in Bad Nauheim, Germany. Each year, scientists and junior researchers get together at this meeting to discuss a broad variety of topics related to lung diseases. The highlights of this event are short presentations and poster sessions on several disease areas.

For this year’s meeting, two Fraunhofer ITEM scientists have been selected to give an oral presentation each: Olaf Holz in the disease area Chronic Obstructive Pulmonary Disease (COPD) and Benedikt Jäger in the disease area Diffuse Parenchymal Lung Disease (DPLD). Furthermore, several scientists of Fraunhofer ITEM have been invited to present their posters among the top ten posters in two disease areas.


Plenary session talks:

“Diffuse Parenchymal Lung Disease”

Benedikt Jäger (Fraunhofer ITEM)
Date and time: February 8, 2018, 8:50 AM to 9:25 AM

Selected as one of the highlight lectures in the Disease Area

“Chronic Obstructive Pulmonary Disease”

Olaf Holz (Fraunhofer ITEM)
Date and time: February 8, 2018, 11:35 AM to 12:10 AM

Selected as one of the highlight lectures in the Disease Area


Poster presentations:

Disease Area: Asthma and Allergy

Rupintrivir reduced host immune response to RV1B infection ex vivo in HDM-sensitized lung tissue.
Author: Olga Danov

Ex-vivo RSV infection and inflammatory response in human and non-human primate precision-cut lung slices (PCLS).
Author: Elaine Twisterling

Breath VOC patterns in adult asthma patients of the ALLIANCE cohort.
Author: Olaf Holz

Measurement of volatile organic compounds (VOCs) in exhaled air of children of the DZL ALL Age asthma cohort (ALLIANCE)
Author: Maximilian Ehrmann, Olaf Holz (presenter)

Selected as one of the top ten posters in the Disease Area “Asthma and Allergy”


Disease Area: Pneumonia and Acute Lung Injury

Reduced oxygenation capacity of RDS can be achieved by repetitive saline lavages ex vivo.
Author: Dorothee Walter


Disease Area: Diffuse Parenchymal Lung Disease

Specific induction of pro-fibrotic biomarker in human ex vivo lung tissue slices.
Author: Christina Hesse

CXCR4 Inhibition by the ibody AD114 blocks bronchosphere formation in a 3D organoid model.
Author: Benedikt Jäger

Potential role of NLRP3 inflammasome and IL‐1β pathway in granuloma generation of sarcoidosis.
Author: Benedikt Jäger

A new humanized mouse model for idiopathic pulmonary fibrosis (IPF).
Author: Linda Plappert


Disease Area: Lung Cancer

Modulation of cancer cell growth and tumor-microenvironmental factors in ex vivo co-cultures of fresh human lung tissue and patient-derived, disseminated cancer cells
Author: Sebastian Konzok
Selected as one of the top ten posters in the Disease Area “Lung Cancer”


Disease Area: Chronic Obstructive Pulmonary Disease (COPD)

A novel demonstration of macrophage plasticity in an integrated human viable lung slice system.
Author: Helena Obernolte
Selected as one of the top ten posters in the Disease Area “Chronic Obstructive Pulmonary Disease (COPD)”

Validation of cell analysis by chip cytometry in induced sputum cells.
Author: Saskia Carstensen

Evidence for metabolic syndrome and insulin resistance in smokers with COPD from serum metabolite analysis at rest and during exercise.
Author: Olaf Holz

A comprehensive way to rate sputum quality in clinical trials
Author: Frauke Pedersen, Olaf Holz (Last Author)


Disease Area: Platform Imaging

Hyperpolarized 129Xe functional MR imaging to monitor the response of human lungs after segmental lipopolysaccharide challenge
Author: Agiolo Luitger Kern, Prof. Dr. Jens Hohlfeld (Co-Author)
Selected as one of the top ten posters in the Disease Area “Platform Imaging”

Please find here the complete program of the DZL Annual Meeting 2018.


    February 8 and 9, 2018


    Bad Nauheim, Germany